Publications
Parkin-dependent mitophagy occurs via proteasome-dependent steps sequentially targeting separate mitochondrial sub-compartments for autophagy
Anna Lechado-Terradas, Sandra Schepers, Katharina I Zittlau, Karan Sharma, Orkun Ok, Julia C Fitzgerald, Stefan Geimer, Benedikt Westermann, Boris Macek, Philipp J Kahle.
PMID: 40396016 PMCID: PMC11864704 DOI: 10.1080/27694127.2022.2143214
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- Written by: Dr. Regina Grupp
- Hits: 29
Neurodegeneration and Neuroinflammation in Parkinson's Disease: a Self-Sustained Loop.
Arena G, Sharma K, Agyeah G, Krüger R, Grünewald A, Fitzgerald JC.
Curr Neurol Neurosci Rep. 2022 Aug;22(8):427-440. doi: 10.1007/s11910-022-01207-5.
Epub 2022 Jun 8. PMID: 35674870 Free PMC article. Review.
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- Written by: Dr. Regina Grupp
- Hits: 27
When mitochondria fall apart: Unbalanced mitochondrial segregation triggers loss of mtDNA in the absence of mitochondrial fusion
Lisa Dengler, Francesco Padovani, Bianca Lemke, Rebecca Brugger, Benedikt Westermann, Boris Maček, Kurt M. Schmoller, Jennifer C. Ewald
bioRxiv preprint doi: https://doi.org/10.1101/2025.05.13.653688; this version posted May 13, 2025
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- Written by: Dr. Regina Grupp
- Hits: 122
Proteome dynamics in iPSC-derived human dopaminergic neurons
Claudia Cavarischia-Rega, Karan Sharma, Julia C. Fitzgerald and Boris Macek
Available online 7 September 2024, Molecular & cellular proteomics: MCP 100838.
https://doi.org/10.1016/j.mcpro.2024.100838
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- Written by: Dr. Regina Grupp
- Hits: 463
A Novel PINK1 p.F385S Loss-of-Function Mutation in an Indian Family with Parkinson's Disease
Karan Sharma MSc, Asha Kishore MD, Anna Lechado-Terradas PhD, Raffaele Passannanti PhD, Francesco Raimondi PhD, Marc Sturm PhD, Ashwin Ashok Kumar Sreelatha MSc, MTech, Divya Kalikavila Puthenveedu MD, Gangadhara Sarma MD, Nicolas Casadei PhD, Rejko Krüger MD, Thomas Gasser MD, Philipp Kahle PhD, Olaf Riess MD, Julia C. Fitzgerald PhD, Manu Sharma PhD.
08 April 2024, Movement Disorders, open access: https://doi.org/10.1002/mds.29792
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- Written by: Dr. Regina Grupp
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The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension.
Katharina Sporbeck, Maximilian L. Haas, Carmen J. Pastor-Maldonado, David S. Schüssele, Catherine Hunter, Zsuzsanna Takacs, Ana L. Diogo de Oliveira, Mirita Franz-Wachtel, Chara Charsou, Simon G. Pfisterer, Andrea Gubas, Patricia K. Haller, Roland L. Knorr, Manuel Kaulich, Boris Macek, Eeva-Liisa Eskelinen, Anne Simonsen & Tassula Proikas-Cezanne
24 Aug 2023, Commun Biol 6, 872 (2023). https://doi.org/10.1038/s42003-023-05236-9
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- Written by: Dr. Regina Grupp
- Hits: 881